Sync for Science

Sync for Science (S4S), launched in 2016, is a public-private collaboration to develop a simplified, scalable, and secure way for individuals to access and share their health data with scientific researchers in support of the Precision Medicine Initiative® (PMI) and NIH’s All of Us Research ProgramAll of Us is a historic effort to gather data from one million people living in the United States to accelerate research and improve health.

S4S leverages and builds upon open source standards such Health Level Seven International (HL7®) Fast Healthcare Interoperability Resources (FHIR®) and OAuth 2.0 allowing an individual to securely share data defined by the Common Clinical Data Set (CCDS), via an application programming interface (API). Ultimately, S4S aims to lower the barriers for electronic health record (EHR) developers to participate in a mobile application (app) ecosystem, and accelerate and guide national priorities for individual-mediated data access and sharing through APIs.

Four major EHR developers are participating in S4S, including Allscripts, Cerner, eClinicalWorks, and Epic. ONC is actively working with new EHR developers and other offices in the Department of Health and Human Services to expand participation in this important initiative – especially in underserved communities serviced by Federally Qualified Health Centers.


For additional resources related to S4S:

Sync for Science API Privacy and Security

An independent testing, analysis, and assessment of  a voluntary subset of S4S pilot organization implementations of the S4S API. Read to learn more about some key privacy and security considerations for healthcare APIs, informed by project activities. 

Content last reviewed on July 24, 2019
Was this page helpful?