The Office of the National Coordinator for Health Information Technology (ONC) is hosting the Advancing Interoperability: Social Determinants of Health Workshop, a one day virtual workshop on Monday, September 21, 2020. As part of ONC’s collaborative approach for Social Determinants of Health (SDOH), the objective of this workshop is to gather health care and human services providers from various professional societies to understand their approaches to integrating SDOH data into value-base care and to discuss tools to accomplish these goals and the challenges to reaching them. This workshop will also provide stakeholders information and tools needed for the development of the social determinants of health data management in clinical practice guidelines and maintenance of certification activities. In the fall of 2019, four new Interoperability Needs were added to Section I: Social, Psychological, and Behavioral Data representing drug use, food insecurity, housing insecurity, and transportation insecurity of the Interoperability Standards Advisory (ISA). Many of the standards or specifications are at production for the implementation maturity level and are still requesting feedback. Incorporating social determinants of health such as those included in the ISA in health care models is of increased interest when it comes to value-based payments. More payers are developing novel ways to address SDOH issues, however providers still struggle with the collection of SDOH data and how to use and share the data in an interoperable and beneficial way that is not burdensome. This workshop will provide attendees the opportunity to share any advancements in standards that are being used which may or may not include standards included in the ISA.