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AJCC N Category
For both Clinical (cN), Pathological (pN) and Neoadjuvant (ycN or ypN), the N Category is defined as Cancer in the regional lymph nodes as defined for each cancer site, including • absence or presence of cancer in regional node(s), and/or • number of positive regional nodes, and/or • involvement of specific regional nodal groups, and/or • size of nodal metastasis or extension through the regional node capsule, and/or • In-transit and satellite metastases, somewhat unique manifestations of nonnodal intralymphatic regional disease, usually found between the primary tumor site and draining nodal basins. Regional Lymph Node (N) Categories Categorizing regional lymph node involvement depends on its existence and extent. NX No information about the N category for the regional lymph nodes, or it is unknown or cannot be assessed N0 No regional lymph node involvement with cancer and for some disease sites, nonnodal regional disease as noted earlier N1, N2, or N3 Evidence of regional node(s) containing cancer, with • an increasing number, and/or • regional nodal group involvement, and/or • size of the nodal metastatic cancer deposit, or • non-nodal regional disease as noted earlier for melanoma and Merkel cell carcinoma, and for colorectal carcinoma


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