Interoperability Standards Advisory (ISA)

isa-gearThe Interoperability Standards Advisory (ISA) process represents the model by which the Office of the National Coordinator for Health Information Technology (ONC) will coordinate the identification, assessment, and determination of "recognized" interoperability standards and implementation specifications for industry use to fulfill specific clinical health IT interoperability needs.

News & Updates

The 2024 ISA Reference Edition is here! View the PDF version here.

The public comment period for the 2024 Standards Version Advancement Process (SVAP) is now open! ONC is considering all comments submitted to the SVAP standards page between now and May 21 at 11:59 PM ET. New standards versions are listed as ‘New Version Under Consideration.’ A user account is required to submit comments for the SVAP. Create a user account by clicking the Log In button located at the top right of the SVAP standards page,



About ISA

The ISA is frequently updated to include improvements made based on recommendations received from public comments and subject matter expert feedback. Read more about the ISA's purpose and scope.



ISA Structure

The ISA is organized and structured into four sections - read more about the ISA's structure and informative characteristics about standards/implementation specifications.


Table of Contents

The Table of Contents of ISA's sections.



ISA Publications

View the most recent and historical ISA publications.


Recent Updates

Check here regularly for the latest updates to the ISA.


Timeline and Comment Process

Learn more about the ISA's annual timeline and how to comment.



View a list of frequently asked questions and answers on the ISA.